The incidence of hepatocellular carcinoma (HCC) has risen as a result of the increased global burden of chronic liver disease due to hepatitis B and C virus infections, aflatoxins B1, alcoholism, and nonalcoholic fatty liver disease associated with the metabolic syndrome and liver infection. Chronic infection with HCV damages the liver and can cause liver failure over time. Hepatitis' means inflammation of the liver. HCV is one of several viruses that can cause hepatitis. HCV is a member of the Flaviviridae family of viruses. Viruses belonging to this family all have ribonucleic acid (RNA) as their genetic material. All hepatitis C viruses are made up of an outer coat (envelope) and contain enzymes and proteins that allow the virus to reproduce within the cells of the body, in particular, the cells of the liver.

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